Chemical Properties:
Package: Bottle, 25kg/Drum, 200kg/Drum, or according to customer's requirement. Storage Condition: Keep the container tightly closed and store in a cool, dry and well-ventilated warehouse away from incompatible substances. Protect from light and moisture. Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery. Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of Phenyl Chloroformate (CAS: 1885-14-9) with high quality. Ruifu Chemical can provide worldwide delivery, competitive price, excellent service, small and bulk quantities available. Purchase Phenyl Chloroformate, Please contact: alvin@ruifuchem.comDescription:
Package/Storage/Shipping:
Chemical Name | Phenyl Chloroformate |
Synonyms | Chloroformic Acid Phenyl Ester; PCF |
Stock Status | In Stock, Commercial Production |
CAS Number | 1885-14-9 |
Molecular Formula | C7H5ClO2 |
Molecular Weight | 156.57 g/mol |
Boiling Point | 187℃ |
Flash Point | 76℃(169°F) |
Sensitive | Moisture Sensitive, Heat Sensitive |
Water Solubility | Hydrolysis |
Solubility | Soluble in Benzene, Chloroform, Ether |
COA & MSDS | Available |
Sample | Available |
Origin | Shanghai, China |
Brand | Ruifu Chemical |
Advantages:
How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals. Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc. Advantages? Superior quality, affordable price, professional services and technical support, fast delivery. Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc. Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers. Factory Audit? Factory audit welcome. Please make an appointment in advance. MOQ? No MOQ. Small order is acceptable. Delivery Time? If within stock, three days delivery guaranteed. Transportation? By Express (FedEx, DHL), by Air, by Sea. Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided. Custom Synthesis? Can provide custom synthesis services to best fit your research needs. Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.FAQ:
Stable Supply: Maintain reasonable stock
Professional Service: One stop purchasing service
Technical Support: Technology solution available
Custom Synthesis Service: Ranged from grams to kilos
Fast Delivery: If within stock, three days delivery guaranteed
High Quality: Established a complete quality assurance system
Sufficient Capacity: Sufficient facilities and technicians
OEM Package: Custom package and label available
Specifications:
Items | Inspection Standards | Results |
Appearance | Colorless Oily Liquid (Visual) | Colorless Oily Liquid |
Purity / Analysis Method | ≥99.0% (GC) | 99.6% |
Phenol | ≤0.20% (GC) | 0.10% |
Diphenyl Carbonate | ≤0.20% (GC) | 0.04% |
Phosgene | ≤0.05% | <0.05% |
Hydrogen Chloride | ≤0.10% | <0.10% |
Density (20℃) | 1.243~1.249 | Complies |
Refractive Index n20/D | 1.510~1.513 | Complies |
Color | ≤50 APHA | Complies |
Infrared Spectrum | Conforms to Structure | Complies |
Conclusion | The product has been tested & complies with the given specifications |
1885-14-9 - Risk and Safety:
1885-14-9 - Application:
Hazard Symbols T+ - Very toxic Risk Codes R22 - Harmful if swallowed R26 - Very Toxic by inhalation R34 - Causes burns R41 - Risk of serious damage to eyes R38 - Irritating to the skin R29 - Contact with water liberates toxic gas R37 - Irritating to the respiratory system Safety Description S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S28 - After contact with skin, wash immediately with plenty of soap-suds. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S28A - UN IDs UN 2746 6.1/PG 2 WGK Germany 3 RTECS FG3850000 FLUKA BRAND F CODES 10-19-21 TSCA Yes Hazard Class 6.1 Packing Group II Toxicity LD50 orally in Rabbit: 1730 mg/kg LD50 dermal Rabbit 4880 mg/kgPhenyl Chloroformate (CAS: 1885-14-9) is an important organic synthesis intermediate, which is widely used in chemical synthesis and can be used as polymer catalyst, plastic modifier, fiber treatment agent, and intermediate of medicine and pesticide. Phenyl Chloroformate acts as a precursor of phenyl mixed anhydrides which are used in peptide coupling reactions. Phenyl Chloroformate serves as a dehydrating reagent for the conversion of primary amides to nitriles and an intermediate in the synthesis of pharmaceuticals and carbamates.1885-14-9 - General Description:
Phenyl Chloroformate appears as a colorless liquid with a strong odor. Corrosive. Toxic by ingestion, inhalation and skin absorption. Very irritating to skin and eyes. Used as a reagent for organic synthesis.1885-14-9 - Air & Water Reactions:
Emits fumes containing HCl in moist air. Decomposes in water to form HCl.1885-14-9 - Reactivity Profile:
Phenyl Chloroformate is incompatible with strong oxidizing agents, alcohols, amines, alkali. May react vigorously or explosively if mixed with diisopropyl ether or other ethers in the presence of trace amounts of metal salts [J. Haz. Mat., 1981, 4, 291].1885-14-9 - Health Hazard:
TOXIC; inhalation, ingestion or contact (skin, eyes) with vapors, dusts or substance may cause severe injury, burns or death. Contact with molten substance may cause severe burns to skin and eyes. Reaction with water or moist air will release toxic, corrosive or flammable gases. Reaction with water may generate much heat that will increase the concentration of fumes in the air. Fire will produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.1885-14-9 - Fire Hazard:
Combustible material: may burn but does not ignite readily. Substance will react with water (some violently) releasing flammable, toxic or corrosive gases and runoff. When heated, vapors may form explosive mixtures with air: indoors, outdoors and sewers explosion hazards. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapors may travel to source of ignition and flash back. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated or if contaminated with water.1885-14-9 - Production Method:
Phenyl Chloroformate is obtained by reacting phenol with phosgene. Phenol was dissolved in chloroform, and phosgene was introduced under cooling to add equimolar N,N-dimethylaniline Dropwise while stirring at 5-10℃., so that the amount of the absorbed phosgene was equimolar to that of phenol. Then diluted with cold water, the oil layer was separated and washed with dilute hydrochloric acid and water successively. After drying with anhydrous calcium chloride, chloroform was distilled off, and then distilled under reduced pressure to collect a fraction of 74-75℃. (1.73kPa), I .e., Phenyl Chloroformate. The yield was about 90%.